Development and evaluation of exemestane-loaded lyotropic liquid crystalline gel formulations

Development and evaluation of exemestane-loaded lyotropic liquid crystalline gel formulations

Introduction: The use of liquid crystalline (LC) gel formulations for drug delivery has considerably improved the current delivery methods in terms of bioavailability and efficacy. The purpose of this study was to develop and evaluate LC gel formulations to deliver the anti-cancer drug exemestane through transdermal route. Methods: Two LC gel formulations were prepared by phase separation coace...

Identification of Lyotropic Liquid Crystalline Mesophases

Lyotropic Liquid-Crystalline Mesophase of Lithium Triflate−Nonionic Surfactant as Gel Electrolyte for Graphene Optical Modulator

Lithium salt (noncoordinating anions, such as lithium triflate (Ltf)) gel electrolytes may be key for the practical use of electrochemical devices. We introduce a new lyotropic liquid-crystalline (LLC) mesophase using Ltf, a small amount of water (as low as 1.3 water per Ltf), and nonionic surfactant (C18H37(OCH2CH2)10OH, C18E10). The LLC phase forms over a broad range of Ltf/C18E10 mole ratios...

Lyotropic liquid crystalline phases formed in an ionic liquid.

Lyotropic liquid crystalline phases of an amphiphilic block copolymer are constructed and characterized in an ionic liquid with comparison of component and temperature effects.

NMR diffusion studies on lyotropic liquid crystalline systems

The pulsed field gradient fourier transform nuclear magnetic resonance (PFG-FTNMR) method to measure translational diffusion coefficients in multicomponent systems has been applied to amphiphilic molecules forming liquid crystalline phases. By analyzing the concentration dependence of the diffusion coefficients of water and amphiphile in a micellar system of N,N-dimethyldodecy lamine oxide (DDA...